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Presentation comparison
Emergency3 of 6 diagnoses compared
| CriteriaComparison detail | Postpartum psychosisEmergency |
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Psychotic or manic syndrome with abrupt change from baseline in the postpartum period.
Clinical reference — not validated decision support. Review before use.
| Postnatal depressionEmergency |
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| Perinatal OCDEmergency |
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| Bipolar relapseEmergencyNot selected |
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| DeliriumEmergencyNot selected |
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| PTSD after traumatic birthEmergencyNot selected |
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| Why it fits | Rapid-onset confusion, bizarre beliefs, hallucinations, marked mood lability, agitation, severe insomnia days-weeks after birth | Low mood, guilt, anhedonia, anxiety, poor bonding, hopelessness, impaired functioning after birth | Distressing intrusive images/urges of harming baby, compulsive avoidance, checking, reassurance seeking | Reduced need for sleep, overactivity, irritability, grandiosity, mood lability after delivery | Fluctuating attention, confusion, sepsis, haemorrhage, pre-eclampsia/eclampsia, metabolic derangement | Flashbacks, dissociation, panic, avoidance of baby care/hospital triggers |
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| What argues against | Applies to the whole presentationReview locally. | |||||
| Must-not-miss | Risk to mother and infant, infanticidal/suicidal behaviour, severe sleep loss, refusal of care | Suicidality, severe self-neglect, psychotic depression, inability to care for infant | Functional collapse, severe insomnia, hidden distress, comorbid depression | Severe sleep deprivation | ||
| Bedside question | Applies to the whole presentationPsychotic or manic syndrome with abrupt change from baseline in the postpartum period. | |||||
| Immediate action | Applies to the whole presentationStabilise and reassess. | |||||
| Investigations | Applies to the whole presentationGuided by presentation. | |||||
| Mimics / overlap | Applies to the whole presentationReview overlap locally. | |||||
Scroll horizontally to review more candidate differentials. Clinical reference — not validated decision support. Review before use.
Review locally.
Psychotic or manic syndrome with abrupt change from baseline in the postpartum period.
Stabilise and reassess.
Guided by presentation.
Review overlap locally.
Rapid-onset confusion, bizarre beliefs, hallucinations, marked mood lability, agitation, severe insomnia days-weeks after birth
Risk to mother and infant, infanticidal/suicidal behaviour, severe sleep loss, refusal of care
Low mood, guilt, anhedonia, anxiety, poor bonding, hopelessness, impaired functioning after birth
Suicidality, severe self-neglect,
Distressing intrusive images/urges of harming baby, compulsive avoidance, checking, reassurance seeking
Functional collapse, severe insomnia
Safety first. Act early.
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Last updated: Pending review
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Create a concise comparison summary for documentation or handoff.
Source pending review
v10 | Local content only
Last updated: Pending review
| Sepsis, haemorrhage, eclampsia, thromboembolism, thyroid storm/myxoedema, medication toxicity |
| Self-harm, severe avoidance, bonding disruption |