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Presentation comparison
RoutineCovers self-neglect, negative symptoms, impaired judgement, reduced engagement, and medical or medication-related causes.
4 of 8 diagnoses compared
| CriteriaComparison detail | Schizophrenia negative syndromeEmergency |
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Chronicity and psychosis history support primary negative symptoms.
Clinical reference — not validated decision support. Review before use.
| DepressionRoutine |
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| DementiaRoutine |
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| CatatoniaRoutine |
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| AutismRoutineNot selected |
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| Substance use disorderRoutineNot selected |
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| Frontal syndromeRoutineNot selected |
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| Medication sedationRoutineNot selected |
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| Why it fits | Avolition, alogia, flattened affect, social withdrawal, poor self-care | Reduced motivation, engagement, poor hygiene, low energy, social withdrawal | Progressive failure in ADLs, medications, finances, navigation, hygiene | Mutism, staring, refusal, immobility, posturing, profound reduction in intake | Lifelong social-communication differences, adaptive limitations, concrete style | Chaotic lifestyle, repeated crises, function tracks use/withdrawal/recovery cycles | Poor judgement, tactlessness, apathy/disinhibition, new personality change | Slowing, drowsiness, reduced spontaneity, masked facies, rigidity, tremor |
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| What argues against | Applies to the whole presentationReview locally. | |||||||
| Must-not-miss | Catatonia, severe self-neglect, vulnerability, untreated medical illness | Suicidality, psychotic depression, refusal of intake | Wandering, exploitation, medication mismanagement | DVT, dehydration | ||||
| Bedside question | Applies to the whole presentationChronicity and psychosis history support primary negative symptoms. | |||||||
| Immediate action | Applies to the whole presentationStabilise and reassess. | |||||||
| Investigations | Applies to the whole presentationGuided by presentation. | |||||||
| Mimics / overlap | Applies to the whole presentationReview overlap locally. | |||||||
Scroll horizontally to review more candidate differentials. Clinical reference — not validated decision support. Review before use.
Review locally.
Chronicity and psychosis history support primary negative symptoms.
Stabilise and reassess.
Guided by presentation.
Review overlap locally.
Avolition, alogia, flattened affect, social withdrawal, poor self-care
Catatonia, severe self-neglect, vulnerability, untreated medical illness
Reduced motivation, engagement, poor hygiene, low energy, social withdrawal
Suicidality, psychotic depression, refusal of intake
Progressive failure in ADLs, medications, finances, navigation, hygiene
Wandering, exploitation,
Mutism, staring, refusal, immobility, posturing, profound reduction in intake
DVT, dehydration,
Based on current selection
Create a concise comparison summary for documentation or handoff.
Source pending review
v10 | Local content only
Last updated: Pending review
Open a selected differential to review its clinical record.
Based on current selection
Create a concise comparison summary for documentation or handoff.
Source pending review
v10 | Local content only
Last updated: Pending review
| Diagnostic overshadowing, missed pain/psychosis |
| Overdose, exploitation, withdrawal, co-occurring depression/psychosis |
| Safeguarding/exploitation risk, falls, missed tumour/stroke |
| Falls, aspiration, quiet delirium, severe akathisia |