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Compare diagnoses

Side-by-side criteria and differential flags.

Ask this

Which diagnosis best fits duration, episodicity, and exclusions?

A

Major depressive disorder

≥5 of 9 SIG-E-CAPS symptoms for ≥2 weeks; ≥1 must be depressed mood or anhedonia

B

Depressive disorder due to another medical condition

Prominent depressive episode directly attributable to physiological effects of a medical condition

ICD-10 code

AF32.x-F33.x

BF06.31-F06.34

Category

AMood Disorders

BMood Disorders

Core threshold (DSM-5-TR criteria)

AFull criteria not included in this record

BFull criteria not included in this record

Additional criteria

AFull criteria not included in this record

BFull criteria not included in this record

Key features

AA. ≥5 of 9 SIG-E-CAPS symptoms for ≥2 weeks; ≥1 must be depressed mood or anhedonia B. Clinically significant distress or impairment in functioning C. Not attributable to substances or another medical condition

BA. Prominent depressive episode directly attributable to physiological effects of a medical condition B. Not better explained by another mental disorder C. Not occurring exclusively during delirium

Common specifiers

ASingle episode / Recurrent; Mild / Moderate / Severe; With psychotic features; In partial remission / In full remission

BWith depressive features; With major depressive-like episode; With mixed features; With psychotic features

Differential flags

ABipolar I or II disorder (prior manic or hypomanic episode - always ask before treating); Persistent depressive disorder / dysthymia (milder, chronic > 2 years); Grief/bereavement (proportionate; preserved pleasure)

BPrimary MDD (independent of GMC); Adjustment disorder with depressed mood (GMC as stressor, not cause); Substance/medication-induced depressive disorder

Severity specifier

ASupported

BNot listed

Differential review

Differential review