Loading…

Compare diagnoses

Side-by-side criteria and differential flags.

Ask this

Which diagnosis best fits duration, episodicity, and exclusions?

A

Major depressive disorder

≥5 of 9 SIG-E-CAPS symptoms for ≥2 weeks; ≥1 must be depressed mood or anhedonia

B

Premenstrual dysphoric disorder (PMDD)

≥5 symptoms in final week before menses, improve within days of onset, become minimal/absent post-menses

ICD-10 code

AF32.x-F33.x

BF32.81

Category

AMood Disorders

BMood Disorders

Core threshold (DSM-5-TR criteria)

AFull criteria not included in this record

BFull criteria not included in this record

Additional criteria

AFull criteria not included in this record

BFull criteria not included in this record

Key features

AA. ≥5 of 9 SIG-E-CAPS symptoms for ≥2 weeks; ≥1 must be depressed mood or anhedonia B. Clinically significant distress or impairment in functioning C. Not attributable to substances or another medical condition

BA. ≥5 symptoms in final week before menses, improve within days of onset, become minimal/absent post-menses B. ≥1 of: marked affective lability; irritability/anger; depressed mood; marked anxiety/tension C. ≥1 additional symptom: decreased interest; concentration difficulty; lethargy; appetite change; hypersomnia/insomnia; overwhelmed; physical symptoms (bloating, breast tenderness, swelling, weight gain)

Common specifiers

ASingle episode / Recurrent; Mild / Moderate / Severe; With psychotic features; In partial remission / In full remission

BMild / Moderate / Severe; In partial remission; In full remission

Differential flags

ABipolar I or II disorder (prior manic or hypomanic episode - always ask before treating); Persistent depressive disorder / dysthymia (milder, chronic > 2 years); Grief/bereavement (proportionate; preserved pleasure)

BPremenstrual syndrome - below PMDD threshold; MDD with luteal worsening; Bipolar disorder with perimenstrual exacerbation

Severity specifier

ASupported

BSupported

Differential review

Differential review