Neurocognitive & Delirium
Neurocognitive & Delirium
Criteria met for major or mild NCD
Criteria met for major or mild NCD (substantial or modest cognitive decline in ≥1 domain)
B. Clinical features consistent with vascular aetiology: decline in complex attention and executive function; temporal link to cerebrovascular event(s) or neuroimaging evidence of vascular pathology C. Probable: neuroimaging with significant vascular pathology or temporal link to infarct; Possible: no neuroimaging or temporal link but clinical features present D. Disturbance not better explained by another brain disease or systemic disorder
B. Insidious onset and gradual progression in ≥1 cognitive domain (most often episodic memory early) C. Probable AD: genetic mutation or ≥2 declining domains + no mixed aetiology; Possible AD: no genetic evidence or insufficient domains or mixed aetiology present D. Disturbance not better explained by cerebrovascular disease, another NCD, medical condition, or substances
A. Criteria met for major or mild NCD B. Clinical features consistent with vascular aetiology: decline in complex attention and executive function; temporal link to cerebrovascular event(s) or neuroimaging evidence of vascular pathology C. Probable: neuroimaging with significant vascular pathology or temporal link to infarct; Possible: no neuroimaging or temporal link but clinical features present
A. Criteria met for major or mild NCD (substantial or modest cognitive decline in ≥1 domain) B. Insidious onset and gradual progression in ≥1 cognitive domain (most often episodic memory early) C. Probable AD: genetic mutation or ≥2 declining domains + no mixed aetiology; Possible AD: no genetic evidence or insufficient domains or mixed aetiology present
Mild / Major neurocognitive disorder; With behavioural disturbance; Probable vascular NCD; Possible vascular NCD
Mild NCD due to AD; Major NCD due to AD; With behavioural disturbance; Early onset
Alzheimer's disease (memory-predominant; insidious); Lewy body NCD (fluctuation, visual hallucinations, parkinsonism); Normal pressure hydrocephalus (gait + incontinence + cognitive triad)
Vascular dementia (stepwise; vascular risk factors; white matter disease); Lewy body dementia (fluctuating cognition, visual hallucinations, parkinsonism, RBD); Frontotemporal dementia (early behaviour/language; memory spared early)