≥3 of the following within days of stopping/reducing an antidepressant (after ≥1 month use): FINISH symptoms — flu-like; insomnia; nausea; imbalance; sensory disturbances; hyperarousal/anxiety
Prominent depressive episode directly attributable to physiological effects of a medical condition
Symptoms characteristic of a depressive disorder causing clinically significant distress/impairment
≥5 of 9 SIG-E-CAPS symptoms for ≥2 weeks; ≥1 must be depressed mood or anhedonia
Depressed mood most of the day, more days than not, for ≥2 years (≥1 yr children/adolescents)
Hypomanic episode threshold has been met.
≥2 years (≥1 yr children/adolescents) of hypomanic AND depressive symptoms not meeting full episode criteria
≥1 month of ≥1 delusion(s)
Emotional or behavioural symptoms in response to an identifiable stressor, within 3 months of stressor onset
≥6 inattentive symptoms and/or ≥6 hyperactive-impulsive symptoms (≥5 for age ≥17) for ≥6 months, inconsistent with developmental level and negatively impacting activities
≥1 full manic episode (abnormally elevated/expansive/irritable mood + ↑energy, ≥7 days or any duration if hospitalised)
Pervasive pattern of instability of interpersonal relationships, self-image, and affect, with marked impulsivity beginning by early adulthood; ≥5 of 9: frantic efforts to avoid abandonment; unstable intense relationships; identity disturbance; impulsivity in ≥2 damaging areas; suicidal/self-mutilating behaviour; affective instability; chronic emptiness; inappropriate intense anger; transient stress-related paranoia/dissociation
Intoxication: recent cannabis use with clinically significant maladaptive behavioural/psychological changes; Withdrawal: cessation/reduction of heavy prolonged use
Severe recurrent temper outbursts (verbal or behavioural), grossly disproportionate to situation, ≥3×/week
Absent/reduced sexual interest/arousal; ≥3 of: absent/reduced interest in sexual activity; absent/reduced sexual/erotic thoughts or fantasies; no/reduced initiation of sexual activity and unreceptive to partner's attempts; absent/reduced sexual excitement/pleasure during sexual activity in ≥75–100% encounters; absent/reduced sexual interest/arousal in response to any internal/external erotic cues; absent/reduced genital or non-genital sensations during sexual activity in ≥75–100% encounters
Self-reported excessive sleepiness (hypersomnolence) despite main sleep period of ≥7 hrs; ≥1 of: recurrent lapses into sleep during same day; prolonged main sleep episode (>9 hrs) that is non-restorative; difficulty being fully awake after abrupt awakening
Preoccupation with having or acquiring a serious illness
Recurrent failure to resist impulses to steal objects that are not needed for personal use or for their monetary value
Persistently or recurrently deficient (or absent) sexual/erotic thoughts or fantasies AND desire for sexual activity; clinician judges deficiency considering age and general/sociocultural context
Recurrent periods of irrepressible need to sleep, lapsing into sleep, or napping within same day, for ≥3 months; ≥1 of: cataplexy (brief episodes of bilateral muscle tone loss) ≥few times/month; hypocretin deficiency (CSF hypocretin-1 ≤110 pg/mL); REM sleep latency ≤15 min on MSLT (or mean sleep latency ≤8 min with ≥2 sleep-onset REM periods)
Evidence by polysomnography of ≥5 obstructive apnoeas/hypopnoeas per hour of sleep + ≥1 of: nocturnal breathing disturbances (snoring, snorting, gasping, breathing pauses); daytime sleepiness/fatigue/unrefreshing sleep not explained by another disorder; OR ≥15 obstructive apnoeas/hypopnoeas per hour of sleep regardless of accompanying symptoms
Symptoms characteristic of a bipolar/related disorder causing clinically significant distress/impairment
Death of someone close to the bereaved person ≥12 months ago (≥6 months in children/adolescents)
Consistent pattern of inhibited, emotionally withdrawn behaviour toward caregivers; ≥2 of: rarely seeks/responds to comfort when distressed; minimal positive affect; unexplained irritability/sadness/fearfulness
Uninterrupted period of illness including a major mood episode (MDE or manic) concurrent with Schizophrenia Criterion A symptoms