Medications
Antidepressants: SSRIs explained
The most commonly prescribed antidepressant class in Australia — how they work and what to expect.
How long it takes
Most people feel better after 2–4 weeks; it can take 6–8 weeks for the full effect. Keep taking it as prescribed even once you feel well.
What SSRIs are
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed class of antidepressant in Australia, and are usually well tolerated. Examples include sertraline, escitalopram, citalopram, fluoxetine, fluvoxamine and paroxetine.
How they work
SSRIs are thought to work by increasing the activity of serotonin, a chemical messenger involved in mood, emotion and sleep. They treat depression and several anxiety conditions, and they are not addictive.
Side effects and stopping
Early side effects such as trouble sleeping, nausea or dizziness often ease after a few weeks. Do not stop suddenly — when the time is right, the dose is lowered slowly over a few weeks. SSRIs work best alongside counselling, exercise and good sleep.
Where this information comes from
More in Medications
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This sheet is general information, not personal medical advice. Always follow the instructions from your own doctor or pharmacist.