Iron

Overview

Essential trace element required for haemoglobin synthesis. Oral forms are poorly tolerated and require specific acidic environments to absorb. IV forms bypass the gut but carry a risk of hypersensitivity.

Maximum Dose

Max 100-200 mg Elemental Iron per day (PO). Note: 325 mg of Ferrous Sulfate contains only ~100 mg of actual elemental iron.

Clinical Focus

Confirm iron deficiency and likely cause, then choose oral alternate-day dosing or IV iron based on severity, tolerance, pregnancy trimester, and urgency.

Bottom Line

Iron is first-line treatment for iron deficiency anaemia, but oral formulations cause significant GI intolerance (take on empty stomach with vitamin C) and IV iron carries anaphylaxis risk.

Brand Names

Ferro-gradumet (Sulfate), FGF (with Folate), Maltofer (Polymaltose), Ferrinject (IV)

Oral Routes

Tablets, Oral Liquid (Stains teeth black, use a straw).

Parenteral

Vials for IV infusion.

Prescribing & PBS

Over The Counter (PO). PBS Restricted (IV).

Primary

Iron deficiency anemia (IDA).

Clinical Place

First-line oral replenishment. IV is reserved for patients who fail PO, cannot tolerate the GI side effects, or require rapid Hb restoration pre-surgery/3rd trimester.