Topical/Inhaled Glucocorticoid·Respiratory - Asthma & COPD

Mometasone

Seasonal/perennial allergic rhinitis, nasal polyps, asthma maintenance

Authority requiredPBSSTEROIDNasonex (Nasal), Asmanex (Inhaled), Novasone (Topical)Nasal spray (50 mcg/spray)+2

No source link confirmed for this record yet. Its own source notes are under Additional.

At a glance

Max Dose

800 mcg/day

Half-life

5 h

Systemic Abs.

EXTREMELY LOW

Allergic Rhinitis

1ST LINE

Cautions

Avoid / Cautions

Untreated localized infection of the nasal mucosa (e.g., Herpes simplex). Pregnancy Category B3 (but widely considered safe for severe rhinitis due to zero systemic absorption).

Where it stands

Rapid Summary

Overview

Highly potent glucocorticoid with virtually zero systemic bioavailability. The absolute gold-standard nasal spray for severe allergic rhinitis and nasal polyps.

Clinical Focus

Must be used continuously to prevent rhinitis. PRN use is ineffective.

Bottom Line

Mometasone is a potent corticosteroid available as nasal spray and inhaler for allergic rhinitis and asthma, but systemic absorption at high doses can cause adrenal suppression.

Formulation & Access

Brand Names

Nasonex (Nasal), Asmanex (Inhaled), Novasone (Topical)

Routes

Nasal spray (50 mcg/spray). Dry powder inhaler. Topical creams/ointments.

Prescribing & PBS

Nasonex is Over The Counter (S2). Asmanex is Authority Required (PBS).

Indications & Use

Primary

PBSTGA

Seasonal/perennial allergic rhinitis, nasal polyps, asthma maintenance.

Clinical Place

First-line therapy for moderate-to-severe hayfever. Vastly superior to oral antihistamines for nasal congestion.

Quick reference

Class & Role

Topical/Inhaled Glucocorticoid — Highly potent glucocorticoid with virtually zero systemic bioavailability.

Route / Formulation

Nasal spray (50 mcg/spray). Dry powder inhaler. Topical creams/ointments. (Nasonex (Nasal), Asmanex (Inhaled), Novasone (Topical))

Usual Dose & Max

Nasal 2 sprays into each nostril OD (200 mcg/day). Once controlled, reduce to 1 spray OD. Max 800 mcg/day (Inhaled for asthma).

Key Indication Doses

Allergic Rhinitis / Hayfever: Nasal 2 sprays into each nostril OD (200 mcg/day). Once controlled, reduce to 1 spray OD. Asthma Maintenance: Inhaled 200-400 mcg OD (often in the evening).

Best Uses

Mometasone is a potent corticosteroid available as nasal spray and inhaler for allergic rhinitis and asthma, but systemic absorption at high doses can cause adrenal suppression.

Key Risks

Respiratory (Nasal): Epistaxis (nosebleeds), nasal irritation, mucosal ulceration. Endocrine: Systemic adrenal suppression is negligible.

Key Interactions

No clinically significant interactions for the nasal spray.

Monitoring

Teach correct nasal spray technique to avoid epistaxis.

Clinical Pearl

If patients point the spray directly up the middle of their nose, the steroid hits the nasal septum, thinning the blood vessels and causing severe, chronic nosebleeds. Instruct them to point the nozzle OUTWARDS toward the ear (the lateral turbinates) to prevent bleeding and maximize absorption.

Access

Authority requiredNasonex (Nasal), Asmanex (Inhaled), Novasone (Topical)

Brand: Nasonex (Nasal), Asmanex (Inhaled), Novasone (Topical)
PBS status: Authority required

From this page

No calculator, monitoring schedule or factsheet is linked to this medicine page yet.

Topical/Inhaled Glucocorticoid·Respiratory - Asthma & COPD

Mometasone

Seasonal/perennial allergic rhinitis, nasal polyps, asthma maintenance

Authority requiredPBSSTEROIDNasonex (Nasal), Asmanex (Inhaled), Novasone (Topical)Nasal spray (50 mcg/spray)+2

No source link confirmed for this record yet. Its own source notes are under Additional.

At a glance

Max Dose

800 mcg/day

Half-life

5 h

Systemic Abs.

EXTREMELY LOW

Allergic Rhinitis

1ST LINE

Cautions

Avoid / Cautions

Untreated localized infection of the nasal mucosa (e.g., Herpes simplex). Pregnancy Category B3 (but widely considered safe for severe rhinitis due to zero systemic absorption).

Where it stands

Rapid Summary

Overview

Highly potent glucocorticoid with virtually zero systemic bioavailability. The absolute gold-standard nasal spray for severe allergic rhinitis and nasal polyps.

Clinical Focus

Must be used continuously to prevent rhinitis. PRN use is ineffective.

Bottom Line

Mometasone is a potent corticosteroid available as nasal spray and inhaler for allergic rhinitis and asthma, but systemic absorption at high doses can cause adrenal suppression.

Formulation & Access

Brand Names

Nasonex (Nasal), Asmanex (Inhaled), Novasone (Topical)

Routes

Nasal spray (50 mcg/spray). Dry powder inhaler. Topical creams/ointments.

Prescribing & PBS

Nasonex is Over The Counter (S2). Asmanex is Authority Required (PBS).

Indications & Use

Primary

PBSTGA

Seasonal/perennial allergic rhinitis, nasal polyps, asthma maintenance.

Clinical Place

First-line therapy for moderate-to-severe hayfever. Vastly superior to oral antihistamines for nasal congestion.

Quick reference

Class & Role

Topical/Inhaled Glucocorticoid — Highly potent glucocorticoid with virtually zero systemic bioavailability.

Route / Formulation

Nasal spray (50 mcg/spray). Dry powder inhaler. Topical creams/ointments. (Nasonex (Nasal), Asmanex (Inhaled), Novasone (Topical))

Usual Dose & Max

Nasal 2 sprays into each nostril OD (200 mcg/day). Once controlled, reduce to 1 spray OD. Max 800 mcg/day (Inhaled for asthma).

Key Indication Doses

Allergic Rhinitis / Hayfever: Nasal 2 sprays into each nostril OD (200 mcg/day). Once controlled, reduce to 1 spray OD. Asthma Maintenance: Inhaled 200-400 mcg OD (often in the evening).

Best Uses

Mometasone is a potent corticosteroid available as nasal spray and inhaler for allergic rhinitis and asthma, but systemic absorption at high doses can cause adrenal suppression.

Key Risks

Respiratory (Nasal): Epistaxis (nosebleeds), nasal irritation, mucosal ulceration. Endocrine: Systemic adrenal suppression is negligible.

Key Interactions

No clinically significant interactions for the nasal spray.

Monitoring

Teach correct nasal spray technique to avoid epistaxis.

Clinical Pearl

Access

Authority requiredNasonex (Nasal), Asmanex (Inhaled), Novasone (Topical)

Brand: Nasonex (Nasal), Asmanex (Inhaled), Novasone (Topical)
PBS status: Authority required

From this page

No calculator, monitoring schedule or factsheet is linked to this medicine page yet.