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Topical/Inhaled Glucocorticoid·Respiratory - Asthma & COPD
Seasonal/perennial allergic rhinitis, nasal polyps, asthma maintenance
Max Dose
800 mcg/day
Half-life
5 h
Systemic Abs.
EXTREMELY LOW
Allergic Rhinitis
1ST LINE
Overview
Highly potent glucocorticoid with virtually zero systemic bioavailability. The absolute gold-standard nasal spray for severe allergic rhinitis and nasal polyps.
Maximum Dose
Max 800 mcg/day (Inhaled for asthma). Max 400 mcg/day (Nasal).
Clinical Focus
Must be used continuously to prevent rhinitis. PRN use is ineffective.
Bottom Line
Mometasone is a potent corticosteroid available as nasal spray and inhaler for allergic rhinitis and asthma, but systemic absorption at high doses can cause adrenal suppression.
Brand Names
Nasonex (Nasal), Asmanex (Inhaled), Novasone (Topical)
Routes
Nasal spray (50 mcg/spray). Dry powder inhaler. Topical creams/ointments.
Prescribing & PBS
Nasonex is Over The Counter (S2). Asmanex is Authority Required (PBS).
Primary
Seasonal/perennial allergic rhinitis, nasal polyps, asthma maintenance.
Clinical Place
First-line therapy for moderate-to-severe hayfever. Vastly superior to oral antihistamines for nasal congestion.