Biphasic Insulin·Endocrinology - Insulins & Injectables

Novomix 30

Type 1 and Type 2 Diabetes

Authority requiredPBSINSULINNovoMix 30Pre-filled pens (100 U/mL)+2

No source link confirmed for this record yet. Its own source notes are under Additional.

At a glance

Max Dose

Titrated

Caution: Composition

30% FAST / 70% SLOW

Caution: Timing

STRICTLY BD

High risk: Hypo Risk

HIGH MID-DAY

Cautions

Avoid / Cautions

Active hypoglycemia. IV administration (The protamine crystals will cause massive fatal microemboli in the blood). Pregnancy Category A.

Where it stands

Rapid Summary

Overview

Pre-mixed biphasic insulin. Contains 30% rapid-acting insulin (Aspart) to cover the meal, and 70% intermediate-acting insulin (Protamine Aspart) to provide background coverage.

Clinical Focus

The patient is locked into a rigid eating schedule. Because the 70% slow portion peaks later in the day, if they skip lunch, they will suffer a severe hypo.

Bottom Line

Novomix 30 is a biphasic insulin combining rapid and intermediate-acting components for simplified regimens, but offers less flexibility than basal-bolus and increases hypoglycaemia risk.

Formulation & Access

Brand Names

NovoMix 30

Parenteral

Pre-filled pens (100 U/mL). Cloudy, white suspension. MUST BE ROLLED/MIXED before injection.

Prescribing & PBS

Authority Required (PBS).

Indications & Use

Primary

PBSTGA

Type 1 and Type 2 Diabetes.

Clinical Place

Used heavily in Type 2 diabetics who require insulin but refuse to do 4 injections a day (Basal-Bolus). Reduces injection burden to 2 per day.

Quick reference

Class & Role

Biphasic Insulin — Pre-mixed biphasic insulin.

Route / Formulation

Pre-filled pens (100 U/mL). Cloudy, white suspension. MUST BE ROLLED/MIXED before injection. (NovoMix 30)

Usual Dose & Max

SC Administered BD (Usually immediately before Breakfast and before Dinner). Doses are titrated to morning and evening BSLs. Titrated based on BSL.

Best Uses

Novomix 30 is a biphasic insulin combining rapid and intermediate-acting components for simplified regimens, but offers less flexibility than basal-bolus and increases hypoglycaemia risk.

Key Risks

Metabolic: Hypoglycemia. The rigid profile makes snacking mandatory. HIGH — Weight gain.

Key Interactions

Beta-blockers, steroids.

Monitoring

Ensure the pen is inverted/rolled 10 times until the cloudy liquid is uniformly white. Injecting the clear liquid at the top gives pure fast insulin (causing a fatal hypo), leaving pure slow insulin at the bottom.

Clinical Pearl

A patient takes NovoMix at 8 AM for breakfast. The 70% slow component peaks right around 1 PM. If they don't eat lunch, they will crash into a severe hypo. They MUST eat 3 meals a day.

Access

Authority requiredNovoMix 30

Brand: NovoMix 30
PBS status: Authority required

From this page

No calculator, monitoring schedule or factsheet is linked to this medicine page yet.

Biphasic Insulin·Endocrinology - Insulins & Injectables

Novomix 30

Type 1 and Type 2 Diabetes

Authority requiredPBSINSULINNovoMix 30Pre-filled pens (100 U/mL)+2

No source link confirmed for this record yet. Its own source notes are under Additional.

At a glance

Max Dose

Titrated

Caution: Composition

30% FAST / 70% SLOW

Caution: Timing

STRICTLY BD

High risk: Hypo Risk

HIGH MID-DAY

Cautions

Avoid / Cautions

Active hypoglycemia. IV administration (The protamine crystals will cause massive fatal microemboli in the blood). Pregnancy Category A.

Where it stands

Rapid Summary

Overview

Pre-mixed biphasic insulin. Contains 30% rapid-acting insulin (Aspart) to cover the meal, and 70% intermediate-acting insulin (Protamine Aspart) to provide background coverage.

Clinical Focus

The patient is locked into a rigid eating schedule. Because the 70% slow portion peaks later in the day, if they skip lunch, they will suffer a severe hypo.

Bottom Line

Novomix 30 is a biphasic insulin combining rapid and intermediate-acting components for simplified regimens, but offers less flexibility than basal-bolus and increases hypoglycaemia risk.

Formulation & Access

Brand Names

NovoMix 30

Parenteral

Pre-filled pens (100 U/mL). Cloudy, white suspension. MUST BE ROLLED/MIXED before injection.

Prescribing & PBS

Authority Required (PBS).

Indications & Use

Primary

PBSTGA

Type 1 and Type 2 Diabetes.

Clinical Place

Used heavily in Type 2 diabetics who require insulin but refuse to do 4 injections a day (Basal-Bolus). Reduces injection burden to 2 per day.

Quick reference

Class & Role

Biphasic Insulin — Pre-mixed biphasic insulin.

Route / Formulation

Pre-filled pens (100 U/mL). Cloudy, white suspension. MUST BE ROLLED/MIXED before injection. (NovoMix 30)

Usual Dose & Max

SC Administered BD (Usually immediately before Breakfast and before Dinner). Doses are titrated to morning and evening BSLs. Titrated based on BSL.

Best Uses

Novomix 30 is a biphasic insulin combining rapid and intermediate-acting components for simplified regimens, but offers less flexibility than basal-bolus and increases hypoglycaemia risk.

Key Risks

Metabolic: Hypoglycemia. The rigid profile makes snacking mandatory. HIGH — Weight gain.

Key Interactions

Beta-blockers, steroids.

Monitoring

Clinical Pearl

A patient takes NovoMix at 8 AM for breakfast. The 70% slow component peaks right around 1 PM. If they don't eat lunch, they will crash into a severe hypo. They MUST eat 3 meals a day.

Access

Authority requiredNovoMix 30

Brand: NovoMix 30
PBS status: Authority required

From this page

No calculator, monitoring schedule or factsheet is linked to this medicine page yet.