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Biphasic Insulin·Endocrinology - Insulins & Injectables
Type 1 and Type 2 Diabetes
Max Dose
Titrated
Composition
30% FAST / 70% SLOW
Timing
STRICTLY BD
Hypo Risk
HIGH MID-DAY
Overview
Pre-mixed biphasic insulin. Contains 30% rapid-acting insulin (Aspart) to cover the meal, and 70% intermediate-acting insulin (Protamine Aspart) to provide background coverage.
Maximum Dose
Titrated based on BSL.
Clinical Focus
The patient is locked into a rigid eating schedule. Because the 70% slow portion peaks later in the day, if they skip lunch, they will suffer a severe hypo.
Bottom Line
Novomix 30 is a biphasic insulin combining rapid and intermediate-acting components for simplified regimens, but offers less flexibility than basal-bolus and increases hypoglycaemia risk.
Brand Names
NovoMix 30
Parenteral
Pre-filled pens (100 U/mL). Cloudy, white suspension. MUST BE ROLLED/MIXED before injection.
Prescribing & PBS
Authority Required (PBS).
Primary
Type 1 and Type 2 Diabetes.
Clinical Place
Used heavily in Type 2 diabetics who require insulin but refuse to do 4 injections a day (Basal-Bolus). Reduces injection burden to 2 per day.