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Stimulant Laxative·Gastrointestinal - Laxatives
Short-term relief of constipation, bowel clearance prior to procedures
Max Dose
15 mg/day
Onset
6-12 h
Dehydration
HIGH RISK
Renal Adj.
NOT REQ.
Overview
Potent prodrug stimulant laxative. Activated by colonic bacteria. Widely used as oral drops for titration on the ward, or in massive doses for colonoscopy bowel prep.
Maximum Dose
Max 15 mg/day (as standard drops). Bowel prep doses are much higher.
Clinical Focus
Highly titratable via liquid drops. Essential to maintain oral hydration during use.
Bottom Line
Sodium picosulfate is a stimulant laxative primarily used for bowel preparation before procedures, but causes significant electrolyte disturbances and dehydration requiring adequate fluid intake.
Brand Names
Dulcolax SP Drops, Picoprep (combo with magnesium citrate)
Oral Routes
Oral liquid drops (7.5 mg/mL). Oral powder sachets (bowel prep).
Prescribing & PBS
Over The Counter (OTC).
Primary
Short-term relief of constipation, bowel clearance prior to procedures.
Clinical Place
Liquid drops allow for very fine titration in the elderly compared to fixed-dose Senna tablets.