Alzheimer's disease (NCD)
Criteria met for major or mild NCD (substantial or modest cognitive decline in ≥1 domain)
Criteria met for major or mild NCD (substantial or modest cognitive decline in ≥1 domain)
Inability to recall important autobiographical information (usually traumatic/stressful) inconsistent with ordinary forgetting; may include dissociative fugue (purposeful travel or bewildered wandering)
Criteria met for major or mild NCD
Criteria met for major or mild NCD
Disturbance of attention (reduced ability to direct, focus, sustain, shift attention) and awareness (reduced orientation to environment)
Persistent difficulty discarding or parting with possessions, regardless of their actual value
Modest cognitive decline in ≥1 domain (concern of individual, knowledgeable informant, or clinician; supported by objective performance evidence)
Substantial cognitive decline in ≥1 domain (complex attention, executive function, learning/memory, language, perceptual-motor, social cognition) based on concern + objective evidence
Criteria met for major or mild NCD
Criteria met for major or mild NCD with insidious onset and gradual progression
≥5 of 9 SIG-E-CAPS symptoms for ≥2 weeks; ≥1 must be depressed mood or anhedonia
Criteria met for major or mild NCD
Criteria met for major or mild NCD
Criteria met for major or mild NCD
Criteria met for major or mild NCD
Hypomanic episode threshold has been met.
Repetitive/persistent pattern of behaviour violating rights of others or major societal norms; ≥3 of 15 criteria in past 12 months (≥1 in past 6): aggression to people/animals; destruction of property; deceitfulness/theft; serious rule violations
≥2 years (≥1 yr children/adolescents) of hypomanic AND depressive symptoms not meeting full episode criteria
≥1 month of ≥1 delusion(s)
Pervasive and excessive need to be taken care of, leading to submissive and clinging behaviour and fears of separation, beginning by early adulthood; ≥5 of 8: difficulty making everyday decisions without advice/reassurance; needs others to assume responsibility for major areas of life; difficulty expressing disagreement out of fear; difficulty initiating projects alone; goes to excessive lengths to obtain nurturance/support; feels uncomfortable/helpless when alone; urgently seeks a replacement relationship when one ends; preoccupied with fears of being left to care for self
Recurrent episodes of incomplete awakening from sleep, usually occurring during the first third of the major sleep episode, accompanied by either sleepwalking (complex behaviour without full consciousness) or sleep terrors (abrupt awakenings with intense fear/autonomic arousal; difficult to console)
Uninterrupted period of illness including a major mood episode (MDE or manic) concurrent with Schizophrenia Criterion A symptoms
≥6 inattentive symptoms and/or ≥6 hyperactive-impulsive symptoms (≥5 for age ≥17) for ≥6 months, inconsistent with developmental level and negatively impacting activities
≥1 full manic episode (abnormally elevated/expansive/irritable mood + ↑energy, ≥7 days or any duration if hospitalised)
Prominent depressive episode directly attributable to physiological effects of a medical condition
Over ≥6 months, recurrent and intense sexual arousal from the exposure of one's genitals to an unsuspecting person, as manifested by fantasies, urges, or behaviours
Absent/reduced sexual interest/arousal; ≥3 of: absent/reduced interest in sexual activity; absent/reduced sexual/erotic thoughts or fantasies; no/reduced initiation of sexual activity and unreceptive to partner's attempts; absent/reduced sexual excitement/pleasure during sexual activity in ≥75–100% encounters; absent/reduced sexual interest/arousal in response to any internal/external erotic cues; absent/reduced genital or non-genital sensations during sexual activity in ≥75–100% encounters
Preoccupation with having or acquiring a serious illness
Recurrent failure to resist impulses to steal objects that are not needed for personal use or for their monetary value
Persistently or recurrently deficient (or absent) sexual/erotic thoughts or fantasies AND desire for sexual activity; clinician judges deficiency considering age and general/sociocultural context
Parkinsonian tremor, muscular rigidity, or akinesia developing in association with medication use (most commonly neuroleptic/antipsychotic or dopamine-depleting agent)
Recurrent periods of irrepressible need to sleep, lapsing into sleep, or napping within same day, for ≥3 months; ≥1 of: cataplexy (brief episodes of bilateral muscle tone loss) ≥few times/month; hypocretin deficiency (CSF hypocretin-1 ≤110 pg/mL); REM sleep latency ≤15 min on MSLT (or mean sleep latency ≤8 min with ≥2 sleep-onset REM periods)
Evidence by polysomnography of ≥5 obstructive apnoeas/hypopnoeas per hour of sleep + ≥1 of: nocturnal breathing disturbances (snoring, snorting, gasping, breathing pauses); daytime sleepiness/fatigue/unrefreshing sleep not explained by another disorder; OR ≥15 obstructive apnoeas/hypopnoeas per hour of sleep regardless of accompanying symptoms
Symptoms characteristic of a bipolar/related disorder causing clinically significant distress/impairment
Depressed mood most of the day, more days than not, for ≥2 years (≥1 yr children/adolescents)
Persistent personality disturbance representing a change from the individual's previous characteristic personality pattern
Deliberate and purposeful fire setting on more than one occasion
≥2 of: delusions; hallucinations; disorganised speech; grossly disorganised/catatonic behaviour; negative symptoms — ≥1 must be delusions, hallucinations, or disorganised speech
Repetitive, seemingly driven, and apparently purposeless motor behaviour (e.g. hand shaking/waving, body rocking, head banging, self-biting, hitting own body)
Involuntary movements (tardive dystonia: sustained/repetitive muscle contractions; tardive akathisia: subjective restlessness + repetitive movements) developing in association with neuroleptic use, persisting ≥4 weeks