Erectile dysfunction
≥1 of 3 symptoms on almost all occasions (≥75–100%) of sexual activity: marked difficulty attaining an erection; marked difficulty maintaining an erection until completion of sexual activity; marked decrease in erectile rigidity
≥1 of 3 symptoms on almost all occasions (≥75–100%) of sexual activity: marked difficulty attaining an erection; marked difficulty maintaining an erection until completion of sexual activity; marked decrease in erectile rigidity
Criteria met for major or mild NCD
Intoxication: reversible substance-specific syndrome due to recent ingestion; Withdrawal: substance-specific syndrome due to cessation/reduction after heavy/prolonged use
Persistent deficits in social communication/interaction across multiple contexts (≥3 components: social-emotional reciprocity; nonverbal communicative behaviours; developing/maintaining relationships)
Hypomanic episode threshold has been met.
Disturbances in normal fluency and time patterning of speech inappropriate for age and language skills; ≥1 of: sound/syllable repetitions; sound prolongations; broken words; audible/silent blocking; circumlocutions; words produced with excess physical tension; monosyllabic whole-word repetitions
Repetitive/persistent pattern of behaviour violating rights of others or major societal norms; ≥3 of 15 criteria in past 12 months (≥1 in past 6): aggression to people/animals; destruction of property; deceitfulness/theft; serious rule violations
Either of: marked delay in ejaculation; marked infrequency or absence of ejaculation, on almost all occasions of partnered sexual activity (≥75–100%), without desire for delay
Disturbance of attention (reduced ability to direct, focus, sustain, shift attention) and awareness (reduced orientation to environment)
Over ≥6 months, recurrent and intense sexual arousal from the exposure of one's genitals to an unsuspecting person, as manifested by fantasies, urges, or behaviours
≥1 of: marked delay in, marked infrequency of, or absence of orgasm; markedly reduced intensity of orgasmic sensations — on almost all occasions (≥75–100%) of sexual activity
Absent/reduced sexual interest/arousal; ≥3 of: absent/reduced interest in sexual activity; absent/reduced sexual/erotic thoughts or fantasies; no/reduced initiation of sexual activity and unreceptive to partner's attempts; absent/reduced sexual excitement/pleasure during sexual activity in ≥75–100% encounters; absent/reduced sexual interest/arousal in response to any internal/external erotic cues; absent/reduced genital or non-genital sensations during sexual activity in ≥75–100% encounters
Over ≥6 months, recurrent and intense sexual arousal from either the use of non-living objects or a highly specific focus on non-genital body part(s), as manifested by fantasies, urges, or behaviours
Over ≥6 months, recurrent and intense sexual arousal from touching or rubbing against a non-consenting person, as manifested by fantasies, urges, or behaviours
Persistent or recurrent difficulties with ≥1 of: vaginal penetration during intercourse; marked vulvovaginal or pelvic pain during intercourse or penetration attempts; marked fear/anxiety about vulvovaginal or pelvic pain in anticipation of, during, or as a result of vaginal penetration; marked tensing or tightening of pelvic floor muscles during vaginal penetration attempts
Predominant complaint of dissatisfaction with sleep quantity/quality: ≥1 of: difficulty initiating sleep; difficulty maintaining sleep (frequent awakenings); early morning awakening with inability to return to sleep
Persistently or recurrently deficient (or absent) sexual/erotic thoughts or fantasies AND desire for sexual activity; clinician judges deficiency considering age and general/sociocultural context
Recurrent episodes of incomplete awakening from sleep, usually occurring during the first third of the major sleep episode, accompanied by either sleepwalking (complex behaviour without full consciousness) or sleep terrors (abrupt awakenings with intense fear/autonomic arousal; difficult to console)
Presence of obsessions (recurrent/persistent intrusive thoughts/urges/images + attempts to suppress or neutralise), compulsions (repetitive behaviours/mental acts driven by rigid rules aimed at reducing distress/feared event), or both
≥4 symptoms from: angry/irritable mood (loses temper; touchy/easily annoyed; angry/resentful); argumentative/defiant behaviour (argues with authority; defies rules; deliberately annoys; blames others); or vindictiveness — for ≥6 months, exhibited during interaction with ≥1 non-sibling individual
Recurrent and intense sexual arousal to atypical objects, situations, or individuals, as manifested by fantasies, urges, or behaviours, for ≥6 months
Over ≥6 months, recurrent, intense sexually arousing fantasies, urges, or behaviours involving sexual activity with a prepubescent child or children (generally ≤13 years)
Persistent or recurrent pattern of ejaculation occurring during partnered sexual activity within ≈1 minute of vaginal penetration and before the individual wishes it, on ≥75–100% of occasions
Death of someone close to the bereaved person ≥12 months ago (≥6 months in children/adolescents)
Over ≥6 months, recurrent and intense sexual arousal from the act of being humiliated, beaten, bound, or otherwise made to suffer, as manifested by fantasies, urges, or behaviours
Over ≥6 months, recurrent and intense sexual arousal from physical or psychological suffering of another person, as manifested by fantasies, urges, or behaviours
Difficulties learning and using academic skills despite intervention; ≥1 of 6 symptoms for ≥6 months: inaccurate/slow word reading; difficulty decoding; poor spelling; difficulties with written expression; poor number sense; mathematical reasoning difficulties
Persistent difficulty with speech sound production that interferes with speech intelligibility or prevents verbal communication of messages
Over ≥6 months, recurrent and intense sexual arousal from cross-dressing, as manifested by fantasies, urges, or behaviours
Over ≥6 months, recurrent and intense sexual arousal from observing an unsuspecting person who is naked, in the process of disrobing, or engaging in sexual activity, as manifested by fantasies, urges, or behaviours
Criteria met for major or mild NCD (substantial or modest cognitive decline in ≥1 domain)
Urge to move the legs, usually accompanied by uncomfortable sensations in the legs, that begins or worsens during rest/inactivity, is partially or totally relieved by movement, and occurs primarily in the evening or night
Cessation or reduction of heavy/prolonged alcohol use
Restriction of energy intake → significantly low body weight for age, sex, developmental trajectory, and physical health
≥1 of: delusions; hallucinations; disorganised speech; grossly disorganised/catatonic behaviour
Recurrent binge eating episodes (eating large amount in discrete period + sense of lack of control)
Intoxication: recent cannabis use with clinically significant maladaptive behavioural/psychological changes; Withdrawal: cessation/reduction of heavy prolonged use
Evidence by polysomnography of ≥5 central apnoeas per hour of sleep
≥1 month of ≥1 delusion(s)
Prominent depressive episode directly attributable to physiological effects of a medical condition
Pattern of culturally inappropriate, overly familiar behaviour with relatively unfamiliar adults; ≥2 of: reduced/absent reticence; overly familiar verbal/physical behaviour; diminished checking back with caregiver; willingness to go with unfamiliar adult
Criteria met for major or mild NCD
Excessive anxiety/worry about multiple events/activities, more days than not for ≥6 months
Failure to meet expected developmental milestones in several areas of intellectual functioning; applies to individuals <5 years when severity cannot be reliably assessed
Recurrent outbursts of failure to control aggressive impulses; ≥1 of: verbal aggression or physical aggression toward property/animals/individuals ≥2×/week (on average) for ≥3 months; ≥3 aggressive outbursts involving damage/injury within a 12-month period
Criteria met for major or mild NCD with insidious onset and gradual progression
Recurrent periods of irrepressible need to sleep, lapsing into sleep, or napping within same day, for ≥3 months; ≥1 of: cataplexy (brief episodes of bilateral muscle tone loss) ≥few times/month; hypocretin deficiency (CSF hypocretin-1 ≤110 pg/mL); REM sleep latency ≤15 min on MSLT (or mean sleep latency ≤8 min with ≥2 sleep-onset REM periods)
Criteria met for major or mild NCD
Symptoms characteristic of an anxiety disorder causing clinically significant distress/impairment
Symptoms characteristic of a sexual dysfunction causing clinically significant distress
Recurrent unexpected panic attacks (abrupt surge reaching peak within minutes; ≥4 of 13 symptoms)
Persistent eating of non-nutritive, non-food substances for ≥1 month
Prominent hallucinations or delusions
Recurrent pulling out of one's hair, resulting in hair loss
≥1 somatic symptom that is distressing or results in significant disruption of daily life