Anxiety disorder due to another medical condition
Prominent anxiety, panic attacks, or obsessions/compulsions directly attributable to physiological effects of another medical condition
Anxiety & Fear-BasedF06.4
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Prominent anxiety, panic attacks, or obsessions/compulsions directly attributable to physiological effects of another medical condition
Prominent depressive episode directly attributable to physiological effects of a medical condition
Persistent personality disturbance representing a change from the individual's previous characteristic personality pattern
Prominent hallucinations or delusions
Symptoms characteristic of a somatic symptom/related disorder causing clinically significant distress/impairment
Intoxication: reversible substance-specific syndrome due to recent ingestion; Withdrawal: substance-specific syndrome due to cessation/reduction after heavy/prolonged use
Intoxication: recent cannabis use with clinically significant maladaptive behavioural/psychological changes; Withdrawal: cessation/reduction of heavy prolonged use
≥3 of 12 catatonia symptoms: stupor; catalepsy; waxy flexibility; mutism; negativism; posturing; mannerism; stereotypy; agitation; grimacing; echolalia; echopraxia
Recurrent skin picking resulting in skin lesions
≥1 symptom of altered voluntary motor or sensory function
Marked incongruence between one's experienced/expressed gender and assigned gender, ≥6 months; in adolescents/adults: ≥2 of: incongruence between experienced gender and primary/secondary sex characteristics; strong desire to be rid of primary/secondary sex characteristics; strong desire for sex characteristics of experienced gender; strong desire to be of experienced gender; strong desire to be treated as experienced gender; strong conviction of having typical feelings/reactions of experienced gender
Persistent or recurrent difficulties with ≥1 of: vaginal penetration during intercourse; marked vulvovaginal or pelvic pain during intercourse or penetration attempts; marked fear/anxiety about vulvovaginal or pelvic pain in anticipation of, during, or as a result of vaginal penetration; marked tensing or tightening of pelvic floor muscles during vaginal penetration attempts
Recurrent outbursts of failure to control aggressive impulses; ≥1 of: verbal aggression or physical aggression toward property/animals/individuals ≥2×/week (on average) for ≥3 months; ≥3 aggressive outbursts involving damage/injury within a 12-month period
Persistently or recurrently deficient (or absent) sexual/erotic thoughts or fantasies AND desire for sexual activity; clinician judges deficiency considering age and general/sociocultural context
Presence of obsessions (recurrent/persistent intrusive thoughts/urges/images + attempts to suppress or neutralise), compulsions (repetitive behaviours/mental acts driven by rigid rules aimed at reducing distress/feared event), or both
Intoxication: recent opioid use; Withdrawal: cessation/reduction after heavy prolonged use, or administration of opioid antagonist
Intoxication: recent sedative/hypnotic/anxiolytic use; Withdrawal: cessation/reduction after prolonged heavy use
Persistent difficulties in social use of verbal/nonverbal communication; ≥1 of: deficits in using communication for social purposes; inability to change communication to match context; difficulty following rules for conversations and storytelling; difficulty understanding what is not explicitly stated
Intoxication: recent stimulant use; Withdrawal: cessation/reduction after prolonged heavy use
Exposure to actual/threatened death, serious injury, or sexual violence (same exposure types as PTSD Criterion A)
Marked fear/anxiety about ≥2 of 5 situations: public transport; open spaces; enclosed places; standing in line/crowds; being outside home alone
Recent ingestion of alcohol
Cessation or reduction of heavy/prolonged alcohol use
Criteria met for major or mild NCD (substantial or modest cognitive decline in ≥1 domain)
≥3 of the following within days of stopping/reducing an antidepressant (after ≥1 month use): FINISH symptoms — flu-like; insomnia; nausea; imbalance; sensory disturbances; hyperarousal/anxiety
Eating/feeding disturbance (apparent lack of interest; sensory-based avoidance; concern about aversive consequences) → persistent failure to meet nutritional/energy needs
≥1 of: delusions; hallucinations; disorganised speech; grossly disorganised/catatonic behaviour
Disturbances in normal fluency and time patterning of speech inappropriate for age and language skills; ≥1 of: sound/syllable repetitions; sound prolongations; broken words; audible/silent blocking; circumlocutions; words produced with excess physical tension; monosyllabic whole-word repetitions
≥2 years (≥1 yr children/adolescents) of hypomanic AND depressive symptoms not meeting full episode criteria
Either of: marked delay in ejaculation; marked infrequency or absence of ejaculation, on almost all occasions of partnered sexual activity (≥75–100%), without desire for delay
Disturbance of attention (reduced ability to direct, focus, sustain, shift attention) and awareness (reduced orientation to environment)
≥1 month of ≥1 delusion(s)
Persistent or recurrent experiences of depersonalisation (feelings of unreality/detachment from one's mind/body) and/or derealisation (feelings of unreality of surroundings)
Severe recurrent temper outbursts (verbal or behavioural), grossly disproportionate to situation, ≥3×/week
Inability to recall important autobiographical information (usually traumatic/stressful) inconsistent with ordinary forgetting; may include dissociative fugue (purposeful travel or bewildered wandering)
Disruption of identity characterised by ≥2 distinct personality states/possession experiences with marked discontinuity in sense of self and agency, accompanied by alterations in affect, behaviour, consciousness, memory, perception, cognition, and/or sensory-motor functioning
≥1 of 3 symptoms on almost all occasions (≥75–100%) of sexual activity: marked difficulty attaining an erection; marked difficulty maintaining an erection until completion of sexual activity; marked decrease in erectile rigidity
≥1 of: marked delay in, marked infrequency of, or absence of orgasm; markedly reduced intensity of orgasmic sensations — on almost all occasions (≥75–100%) of sexual activity
Absent/reduced sexual interest/arousal; ≥3 of: absent/reduced interest in sexual activity; absent/reduced sexual/erotic thoughts or fantasies; no/reduced initiation of sexual activity and unreceptive to partner's attempts; absent/reduced sexual excitement/pleasure during sexual activity in ≥75–100% encounters; absent/reduced sexual interest/arousal in response to any internal/external erotic cues; absent/reduced genital or non-genital sensations during sexual activity in ≥75–100% encounters
Excessive anxiety/worry about multiple events/activities, more days than not for ≥6 months
Persistent difficulty discarding or parting with possessions, regardless of their actual value
Preoccupation with having or acquiring a serious illness
Persistent difficulties in acquisition and use of language across modalities (spoken, written, sign, or other) due to deficits in comprehension or production, including reduced vocabulary, limited sentence structure, and impairments in discourse
≥5 of 9 SIG-E-CAPS symptoms for ≥2 weeks; ≥1 must be depressed mood or anhedonia
Criteria met for major or mild NCD
Criteria met for major or mild NCD
Dopamine antagonist exposure (antipsychotic or antiemetic) and development of severe muscle rigidity and elevated temperature
Recurrent episodes of incomplete awakening from sleep, usually occurring during the first third of the major sleep episode, accompanied by either sleepwalking (complex behaviour without full consciousness) or sleep terrors (abrupt awakenings with intense fear/autonomic arousal; difficult to console)
Recurrent unexpected panic attacks (abrupt surge reaching peak within minutes; ≥4 of 13 symptoms)
Single or multiple motor OR vocal tics (but not both motor and vocal) have been present at some time
Depressed mood most of the day, more days than not, for ≥2 years (≥1 yr children/adolescents)
Persistent eating of non-nutritive, non-food substances for ≥1 month
Exposure to actual/threatened death, serious injury, or sexual violence (direct, witnessed, learning about close person, or repeated indirect exposure)
Persistent or recurrent pattern of ejaculation occurring during partnered sexual activity within ≈1 minute of vaginal penetration and before the individual wishes it, on ≥75–100% of occasions
Single or multiple motor and/or vocal tics
Urge to move the legs, usually accompanied by uncomfortable sensations in the legs, that begins or worsens during rest/inactivity, is partially or totally relieved by movement, and occurs primarily in the evening or night
Repeated regurgitation of food for ≥1 month; regurgitated food may be re-chewed, re-swallowed, or spat out
Uninterrupted period of illness including a major mood episode (MDE or manic) concurrent with Schizophrenia Criterion A symptoms
≥2 of: delusions; hallucinations; disorganised speech; grossly disorganised/catatonic behaviour; negative symptoms — ≥1 must be delusions, hallucinations, or disorganised speech
Same symptom criteria as Schizophrenia (≥2 of the 5 symptom clusters; ≥1 must be delusions, hallucinations, or disorganised speech)
Marked fear/anxiety about ≥1 social situation with possible scrutiny by others
≥1 somatic symptom that is distressing or results in significant disruption of daily life
Persistent difficulty with speech sound production that interferes with speech intelligibility or prevents verbal communication of messages
Repetitive, seemingly driven, and apparently purposeless motor behaviour (e.g. hand shaking/waving, body rocking, head banging, self-biting, hitting own body)
Both multiple motor tics AND ≥1 vocal tic present at some time during the illness, though not necessarily simultaneously
Recurrent pulling out of one's hair, resulting in hair loss
Acquisition and execution of coordinated motor skills is substantially below expected for chronological age and opportunity for skill learning
Predominant complaint of dissatisfaction with sleep quantity/quality: ≥1 of: difficulty initiating sleep; difficulty maintaining sleep (frequent awakenings); early morning awakening with inability to return to sleep
Criteria met for major or mild NCD
Self-reported excessive sleepiness (hypersomnolence) despite main sleep period of ≥7 hrs; ≥1 of: recurrent lapses into sleep during same day; prolonged main sleep episode (>9 hrs) that is non-restorative; difficulty being fully awake after abrupt awakening
Criteria met for major or mild NCD with insidious onset and gradual progression
Criteria met for major or mild NCD
Criteria met for major or mild NCD
Repeated episodes of arousal during sleep associated with vocalisation and/or complex motor behaviours
Persistent deficits in social communication/interaction across multiple contexts (≥3 components: social-emotional reciprocity; nonverbal communicative behaviours; developing/maintaining relationships)
≥1 full manic episode (abnormally elevated/expansive/irritable mood + ↑energy, ≥7 days or any duration if hospitalised)
Evidence by polysomnography of ≥5 central apnoeas per hour of sleep
Falsification of physical or psychological signs or symptoms, or induction of injury or disease, associated with identified deception in self (imposed on self) or in another person (imposed on another)
Failure to meet expected developmental milestones in several areas of intellectual functioning; applies to individuals <5 years when severity cannot be reliably assessed
Recurrent periods of irrepressible need to sleep, lapsing into sleep, or napping within same day, for ≥3 months; ≥1 of: cataplexy (brief episodes of bilateral muscle tone loss) ≥few times/month; hypocretin deficiency (CSF hypocretin-1 ≤110 pg/mL); REM sleep latency ≤15 min on MSLT (or mean sleep latency ≤8 min with ≥2 sleep-onset REM periods)
Symptoms characteristic of a feeding/eating disorder causing clinically significant distress/impairment
Criteria met for a personality disorder (enduring pattern of inner experience/behaviour deviating markedly from cultural expectations; pervasive; inflexible; stable; leading to distress/impairment)
Pervasive distrust and suspiciousness of others such that their motives are interpreted as malevolent, beginning by early adulthood; ≥4 of 7: suspects exploitation/harm/deception; preoccupied with unjustified doubts about loyalty; reluctant to confide; reads hidden threatening meanings; bears grudges; perceives attacks on character not apparent to others; recurrent suspicions about fidelity of partner
Prominent hallucinations or delusions
Involuntary movements (tardive dystonia: sustained/repetitive muscle contractions; tardive akathisia: subjective restlessness + repetitive movements) developing in association with neuroleptic use, persisting ≥4 weeks
Restriction of energy intake → significantly low body weight for age, sex, developmental trajectory, and physical health
Recurrent binge eating episodes (eating large amount in discrete period + sense of lack of control)
Abnormal and prolonged contraction of muscles of eyes, face, neck, limbs, or trunk developing in association with medication use
Parkinsonian tremor, muscular rigidity, or akinesia developing in association with medication use (most commonly neuroleptic/antipsychotic or dopamine-depleting agent)
Evidence by polysomnography of ≥5 obstructive apnoeas/hypopnoeas per hour of sleep + ≥1 of: nocturnal breathing disturbances (snoring, snorting, gasping, breathing pauses); daytime sleepiness/fatigue/unrefreshing sleep not explained by another disorder; OR ≥15 obstructive apnoeas/hypopnoeas per hour of sleep regardless of accompanying symptoms
Medication-induced movement symptoms causing clinically significant distress or impairment
Symptoms characteristic of an anxiety disorder causing clinically significant distress/impairment
Symptoms characteristic of a depressive disorder causing clinically significant distress/impairment
Symptoms characteristic of an OCD-related disorder causing clinically significant distress/impairment
Symptoms characteristic of a sexual dysfunction causing clinically significant distress
Symptoms characteristic of a trauma/stressor-related disorder causing clinically significant distress/impairment
Over ≥6 months, recurrent, intense sexually arousing fantasies, urges, or behaviours involving sexual activity with a prepubescent child or children (generally ≤13 years)
Symptoms characteristic of a bipolar/related disorder causing clinically significant distress/impairment